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Post Doc Associate-molecular oncology & translatio

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Job Details
Job Order Number
8041517
Company Name
Ann & Robert H. Lurie Children's Hospital of Chica
Physical Address
225 E Chicago Ave # # 14
Chicago, IL 60611
Job Description

Post Doc Associate-molecular oncology & translational experimental therapeutics
Job Locations

US-IL-Chicago

Requisition ID
2021-15088

Category
Other

Shift
Days

Overview

Our lab is seeking two postdoctoral fellows interested in molecular cancer biology and experimental therapeutics of brain tumors using our large panel of existing (>150) and expanding patient derived orthotopic xenograft (PDOX or orthotopic PDX) mouse models. In addition to the continued development of novel PDOX models, active research projects include the understanding of tumor biology, identifying new diagnostic and/or therapeutic targets and conducting preclinical drug testing for the initiation of clinical trials. The postdoctoral fellows will be actively involved in the collaboration with physicians, pathologists, pharmacologists, bioinformatics and other research personnel.

The postdoc fellows will participate in two active NIH-funded UO1 research projects for the next 4-5 years. The salary and benefit are commensurate with the years of experience by NIH guideline.

Successful candidates must be highly motivated and hold a PhD in biology and/or MD degree. Fresh graduates are encouraged to apply.

For more information about the PI, Dr. Xiao-Nan Li and the lab, please refer to Dr. Li ’s faculty profiles:

https://www.luriechildrens.org/en/research/research-areas/laboratory-research/li-laboratory/

https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=40385

Responsibilities

Undertake an independent research project

  • Analyze data, prepare manuscripts and presentations at local, national and international venues.
  • Participate collaboratively in other research projects
  • Help write grant proposals and progress reports related to research project.
  • Participate in regular lab meetings, journal clubs, research seminars and graduate student training.
  • Undertake an independent research project on laboratory seeking to establish and maintain patient-derived orthotopic xenograft (PDOX) mouse models for leukemia, brain and other solid tumors
  • Undertake an independent research project to understand mechanisms of actions of new chemotherapeutic agents and drug resistance involving cell and molecular biology.
  • Performing independently massive high-throughput drug screening and data analysis.
  • Design and implement research protocols; design safety procedures; adapt new procedures, methods or instrumentation relative to research procedures.
  • Oversee media preparation, animal maintenance and equipment maintenance; quality control analysis of reagents.
  • Collect, prepare and analyze research data;keep a detailed notebook summarizing experiments and recording research data;maintain computer database of research data;tabulate and display data for presentation in research conferences and for manuscript preparation; use graphics and statistical software to analyze and present data.
  • Supervise other personnel in the laboratory to coordinate research efforts for increased efficiency; participate in training of fellows, residents, students and volunteer workers as needed.
  • Search pertinent scientific literature and draft/edit manuscripts.
  • Assist in grant writing.
  • Present data in written and oral form at local and national meetings.
  • Assist with ordering and procurement of supplies and equipment and with general maintenance of laboratory.

Qualifications

  • A level of knowledge normally acquired through the completion of a Ph.D. or M.D.
  • Possess an excellent command of the English language; medical and scientific terminology is required.
  • Organizational skills:
  • Ability to establish priorities and react promptly to a large variety of requests and needs, sometimes in stressful situations.
  • A level of knowledge of cancer biology as well as cell/molecular biology is preferred.
  • Experience in tissue culture techniques and in vitro assays as well as general lab skills strongly preferred.
  • Experience in mouse, handling and procedures (i.v. i.p. and gavage preferred).
  • Good scientific writing ability, oral communication skills, and the ability to work both independently and collegially with colleagues are required.

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