at Northwestern University in Evanston, Illinois, United States
Job Description
Job Opening Id: 49554
Department: MED-Cancer Center
Salary/Grade: NEX/11
Job Summary:
The candidate will be responsible for all stages of histopathology-related tissue processing of non-clinical specimens including: tissue fixation, processing, embedding, microtomy (paraffin, plastic or cryosectioning), standard and special histological staining, as well as quality control. The work involves performing multiple laboratory related duties: tracking job flow, processing paperwork, instrument maintenance and documentation, and communication with client staff and faculty as needed. Experience with immunostaining methods (immunohistochemistry, immunofluorescence, enzyme histochemistry) and nucleic acid in situ hybridization are highly desirable. The work requires ensuring lab compliance with all associated rules and regulations for standard operating procedures and safety regulations. The position will be on-site at the Mouse Histology & Phenotyping Laboratory (MHPL) at the Robert H. Lurie Comprehensive Cancer Center in the Chicago campus of Northwestern University.
Specific Responsibilities:
- Biological specimen tissue processing and grossing for paraffin embedding or frozen block preparations
- Microtomy (paraffin, cryostat and vibratome)
- H&E and specialized histology stains
- Molecular phenotyping: immunohistochemistry, immunofluorescence, ISH/RNAscope
- Provide consultations for MHPL clients regarding tissue harvest, fixation protocols, tissue grossing requirements, histology stains and molecular phenotyping services
- Quality control of tissue sections, histology stains, IHC, IF and RNAscope slides
- Provide training for MHPL instruments for rent: cry
