at Northwestern University in Evanston, Illinois, United States
Job Description
Job Opening Id: 50171
Department: MED-Cancer Center
Salary/Grade: NEX/15
Job Summary:
The candidate will be responsible for all stages of histopathology-related tissue processing of non-clinical specimens including: tissue fixation, processing, embedding, microtomy (paraffin, plastic or cryosectioning), standard and special histological staining, as well as quality control. The work involves performing multiple laboratory related duties: tracking job flow, processing paperwork, instrument maintenance and documentation, and communication with client staff and faculty as needed. Experience with immunostaining methods (immunohistochemistry, immunofluorescence, enzyme histochemistry) and nucleic acid in situ hybridization are highly desirable. The work requires ensuring lab compliance with all associated rules and regulations for standard operating procedures and safety regulations. The position will be on-site at the Mouse Histology & Phenotyping Laboratory (MHPL) at the Robert H. Lurie Comprehensive Cancer Center in the Chicago campus of Northwestern University.
Scientific Responsbilities:
• Biological specimen tissue processing and grossing for paraffin embedding or frozen block preparations
• Microtomy (paraffin, cryostat and vibratome)
• H&E and specialized histology stains
• Molecular phenotyping: immunohistochemistry, immunofluorescence, ISH/RNAscope
• Provide consultations for MHPL clients regarding tissue harvest, fixation protocols, tissue grossing requirements, histology stains and molecular phenotyping services
• Quality control of tissue sections, histology stains, IHC, IF and RNAscope slides
Administration
• Tracking and documentation of MHPL orders
• Maintenance of lab instruments
• Observance of lab compliance to research safety guidelines
• Serve as liaison to the Office of Research Safety
Finance
• Inventory and ordering of lab consumables
• Negotiates purchases with vendors
• Tracking of lab purchases
Supervision
- Provide training for MHPL instruments for rent: cryostat and vibratome
- Training and supervision of lab interns
Miscellaneous
Performs other duties as assigned.
