Research Assistant Professor, Immune Deviation & D

at Ann & Robert H. Lurie Children's Hospital of Chica in Lake Forest, Illinois, United States

Job Description

Ann & Robert H. Lurie Children's Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 140-year legacy of excellence, kids and their families are at the center of all we do. Ann & Robert H. Lurie Children's Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.

LocationSimpson Querrey Biomedical Research Center

Job Description
The Research Assistant Professor will perform lab work in the Immune Deviation & Disease Neighborhood. The lab investigates the role of mast cells and fibroblasts in driving inflammation and scarring in Eosinophilic Esophagitis (EoE). The candidate should be highly motivated with experience working in a translational/basic science laboratory setting using wet lab tools to define biological mechanism ideally associated with mucosal inflammation, allergic inflammation, or fibrosis. The Research Assistant Professor should have considerable experience in all aspects of laboratory immunology and molecular biology research. Design, optimization and execution of experiments aligned with the lab mission and through reading literature is vital. Proficiency in murine skills required: breeding, handling, oral gavage, intraperitoneal administration, cardiac puncture, topical (skin) application, and dissection. Proficiency in spectral flow cytometry is required including use of BD machines (e.g. FACS Symphony A3/A5/S6), high-parameter spectral panel design, troubleshooting, optimization of antibody dilution and gating using FMOs, sorting, and FlowJo analysis.

The candidate should be willing to learn new machines (e.g. BD FACS Discover S8, BD FACS Symphony A5). The candidate should be able to work with research technician to complete experiments. The candidate should be proficient in RNA/DNA/protein isolation, RT-PCR, western blot/ELISA, immunohistochemistry/immunofluorescence, and cell culture including suspension and/or adherent human/murine cells. The candidate should be willing to new techniques (e.g. Crispr, air liquid interface, organoids). The candidate should have a strong ability to troubleshoot and collaborate with faculty members in the performance and analysis of complex research studies and acquisition of new skills. The candidate should be able to coordinate with 1) core facilities, 2) clinical research coordinator and 3) research technician. The candidate should be able to complete mathematical calculations, computer tasks, & assist in judging the validity of data. The candidate should be able to follow protocols, policies, procedures, regulations, good clinical & laboratory practices. Manuscript writing is critical, and the candidate should have interest in grant writing. The candidate will maintain an agenda, lab notebook and project-based PowerPoints which will be presented at lab meeting and seminars.

Assists with the creation, implementation and continuous improvement of the research enterprise by providing coordination and oversight of new and existing research programs and/or projects. Serves as a liaison to investigators across the campus including Stanley Manne Research Center, Northwestern University Feinberg School of Medicine (NUFSM) Departmental, and associated research labs. Supervises lab personnel including research assistants, associates, and post-docs. Manages laboratory funds and grant budgets. The Research Assistant Professor should have a track record of independent research and peer-reviewed publications and a commitment to collaborative and/or independent research. Develops and conducts scholarly research in collaboration with the Division's Medical Director to secure outside grant and contract funds.

Essential Job Functions:

Contributes intellectually and strategically to the development of a thematic research projects related to area of research program.

Design, plan, troubleshoot and execute experiments in an independent manner.

Writes Institutional Board Review (IRB) protocols in order to obtain the aforementioned tissue specimens.

Physically consents potential donors and/or supervising adult.

Writes pertinent protocols that are submitted to and scrutinized by the Institutional Animal Care and Use Committee (IACUC).

Independently writes research manuscripts; provides final approval for such manuscripts; is responsible for the overall editorial process; acts as the corresponding author for all manuscripts; acts as a reviewer for relevant scientific journals; acts an editor for scientific journals.

Writes grants based upon data generated in the laboratory to be applied for funding at the national level.

Writes scientific review articles and book chapters relevant to area of focus.

Presents research findings at regional, national and... For full info follow application link.

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Job Posting: 11879730

Posted On: May 09, 2024

Updated On: Jun 08, 2024

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