at University of Illinois in Urbana, Illinois, United States
Job Description
Research Scientist - Beckman Institute for Advanced Science and TechnologyBeckman Institute for Advanced Science and Technology
Job Summary
Provide hands-on leadership in the design and optimization of reaction conditions, scale up starting materials and purification of final products in support of ongoing research projects and management of automated synthesizer instruments in the Burke laboratory.
Duties & Responsibilities
- Design, synthesize, purify and characterize target molecules of interest.
- Provide oversight, direction and supervision of graduate students, research personnel (including postdoctoral fellows and grad assistants) and undergraduate students in organic and medicinal chemistry research. Provide mentoring of personnel in lab protocol, experimentation methods and project assignments. Oversee both undergraduate and graduate students regarding their scientific progress.
- Collaborate with colleagues in various other Institutions on research initiatives.
- Research manuscripts preparation for publication.
- Utilize and optimize automated laboratory equipment and processes. Stay current with advancements in organic synthesis, laboratory automation, and programming languages.
- Prepare grant applications for submission to the federal government and draft the annual scientific reports for awarded grants.
• PhD in Chemistry or related discipline
• Experience with:
o Designing and synthesis of small molecules for drug discovery
o Performing SAR study based on existing biological data for further lead optimization total synthesis or semi synthesis
o Targeting molecule analysis and purification (TLC, chromatography, analytical and preparative LC-MS, GC-MS, HRMS)
o Developing novel synthesis methods using standard approaches
o Scale-up of organic synthesis reactions and separations, processing and analysis of NMR spectra of target molecule, conducting UV-Vis Spectrophotometry and analysis of the data
o Supporting the preparation of externally reviewed grant proposals
o Providing technical and trouble-shooting support
o Collaboratively solving complex problems in a multi-functional team
o Transferring the establishing method to CRO for manufacturing processes
Preferred Qualifications
• PhD in Organic Chemistry
• Experience with synthesis and purification of kinase inhibitors and related small molecule compounds, computer-aided drug design and optimization, developing novel synthesis methods using innovative approaches
Knowledge, Skills and Abilities
• In-depth understanding of organic synthesis, purification techniques and analysis of organic reactions/products
• Knowledge of key medicinal chemistry concepts
• Good understanding of biology, pharmacology, drug metabolism and pharmacokinetics
Appointment Information
This is a 100% full-time Academic Professional position, appointed on a 12-month basis. The expected start date is as soon as possible after the posting period ends. The salary range for this position is $58,656 - $65,000/year. Final salary offered will be determined by a thorough assessment of available market data, internal salary equity, candidate experience and qualifications, collective bargaining agreements, and budget constraints.
Application Procedures & Deadline Information
Applications must be received by 6:00 pm (Central Time) on August 8, 2024. Apply for this position using the Apply Now button at the top or bottom of this posting. Applications not submitted through https://jobs.illinois.edu will not be considered. For further information about this specific position, please contact jobs@beckman.illinois.edu. For questions regarding the application process, please contact 217-333-2137.
The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify .
Applicants with disabilities are encouraged to apply and may request a reasonable accommodation under the Americans with Disabilities Act (2008) to complete the application and/or interview process. Requests may be submitted through the reasonable accommodations portal , or by contacting the Accessibility & Accommodations Division of the Office for Access and Equity at 217-333-0885, or by emailing accessibility@illinois.edu .
Requisition ID: 1025695
Job Category: Research
Apply at: https://jobs.illinois.edu
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