at Northwestern University in Evanston, Illinois, United States
Job Description
Job Opening Id: 50732
Department: MED-Pharmacology
Salary/Grade: NEX/11
Job Summary:
A Research Technologist 2/3 position is available in the laboratory of Dr. Paul Burridge in the Department of Pharmacology and the Center for Pharmacogenomics at Northwestern University Feinberg School of Medicine, Chicago, IL.
Successful candidates will participate in NIH-funded projects to study the application of human induced pluripotent stem cells (hiPSC) in predictive medicine. Our goal is to develop the next generation of tools for predicting chemotherapy toxicity responses and validating SNPs to allow the use of genomic information in personalized medicine.
We are looking for highly motivated and creative candidates with an interested in the differentiation of patient-specific hiPSC-derived cardiomyocytes and studying their drug response using a variety of biochemical and RNA-seq assays. The role will involve hiPSC culture and cardiac differentiation, assisting with experiments, maintaining detailed records, analyzing expression information, training on a variety of high throughput and high-content screening/imaging platforms. Laboratory consumable ordering will also be part of this role.
Conducts experimental research lab work and/or assists in design of one or more specific phase(s) of entire project(s). May complete mathematical calculations, and/or computer tasks and/or assist in judging validity of data. Follows appropriate protocols, policies, procedures, regulations, Good Clinical and Good Laboratory Practices.
Specific Responsibilities:
- Following protocols, designs, sets-up and conducts basic experiments.
- Analyzes and troubleshoots protocols and data obtained from individual experiments and recommends alternatives and suggestions to improve processes, validity and/or accuracy.
- Using a fully functioning level of skill, completes the following activities
Molecular Biology:
- DNA, RNA, Protein isolation, purification and expression
- PCR, RT-PCR
- Recombinant virus production and purification
